Runwei Yang (杨润威), MD, Postdoc Associate, email: yangrunwei AT uchicago.edu

Runwei obtained an M.D. from Southern Medical University in 2020, where he received eight-year medical education and investigated the copy number variations of glioblastoma by single-cell RNA-seq under the guidance of Prof. Songtao Qi and researcher Yawei Liu. He is interested in uncovering the mechanism of brain diseases and thereby developing potential therapies. In Zhang Lab, Runwei focuses on brain organoids and alternative splicing dynamics in brain disorders.

Representative publications (*Co-first authors) :

  1. Yang R*, Feng X*, Arias-Cavieres A, Mitchell RM, Polo A, Hu K, Zhong R, Qi C, Zhang RS, Westneat N, Portillo CA, Nobrega MA, Hansel C, Garcia Iii AJ, Zhang X. Upregulation of SYNGAP1 expression in mice and human neurons by redirecting alternative splicing. Neuron. 2023;111(10):1637-50.

  2. Yang Y*, Yang R*, Kang B, Qian S, He X†, Zhang X.† Single-cell long-read sequencing in human cerebral organoids uncovers cell-type-specific and autism-associated exons Cell Reports. 2023;42(11): 113335.

  3. Runwei Yang*, Guanglong Huang*, Jinglin Guo*, Yaomin Li, Haimin Song, Kaishu Li, Guozhong Yi, Zhiying Lin, Xiran Wang, Sidi Xie, Zhifeng Liu, Xiaofeng Shi, Ke Li, Songtao Qi#, Yawei Liu#. Genetic characterization of stem cell-like cancer cell in the peri-tumoral regions and proliferative lymphocyte in the peripheral blood of patients with glioblastoma. bioRxiv. 2020. DOI: https://doi.org/10.1101/2020.01.06.895987.

  4. Runwei Yang*,Jinglin Guo*,Zhiying Lin,Haimin Song,Zhanpeng Feng,Yichao Ou,Mingfeng Zhou,Yaomin Li,Guozhong Yi,Ke Li,Kaishu Li,Manlan Guo,Xiran Wang,Guanglong Huang,Zhifeng Liu,Songtao Qi#,Yawei Liu#. The combination of two-dimensional and three-dimensional analysis methods contributes to the understanding of glioblastoma spatial heterogeneity. Journal of Biophotonics. 2020. DOI: 10.1002/jbio.201900196.

  5. Zhiying Lin*, Runwei Yang*, Kaishu Li, Guozhong Yi, Zhiyong Li, Jinglin Guo, Zhou Zhang, Peng Junxiang, Yawei Liu, Songtao Qi# & Guanglong Huang#. Establishment of age group classification for risk stratification in glioma patients. BMC Neurology. 2020. DOI: 10.1186/s12883-020-01888-w.